Major Medical Devices

Standard endovascular repair of an abdominal aortic aneurysm needs large devices delivered through both groins, which rules out many patients with small or diseased vessels. AxSES is an ultra-low-profile stent graft delivered from one puncture in the shoulder area, in the direction of natural blood flow.

Endovascular repair is the standard of care for abdominal aortic aneurysm, and it is built around devices too large for a significant share of the people who need them. Delivery requires two groin punctures and navigation against the direction of blood flow, so patients with small or calcified vessels, disproportionately women and patients with more complex anatomy, are pushed towards more invasive surgery or excluded altogether.

AxSES was designed around that constraint rather than adapted to it. A much lower-profile graft goes in through a single small artery in the arm or shoulder and travels with the blood flow instead of against it, removing both groin punctures from the procedure. The team behind it includes engineers and clinicians who have brought previous vascular platforms to market, and the intellectual property covers the access route itself.